Stiff-Person Vereinigung Deutschland - Hilfe für SPS-Kranke  Titel
STIFF–PERSON VEREINIGUNG DEUTSCHLAND E.V. ⊃⊂ 52372 Kreuzau-Stockheim, Raiffeisenstraße 50 ⊃⊂ Tel. 02421 504357

Therapeutische Möglichkeiten für Patienten mit Stiff-Person-Syndrom
(Quelle: El-Abassi: SPS: Understanding...)(El-Abassi, Rima, et al.: SPS: Understanding the complexity. In: Journal of the Neurological Sciences 404 (2019) 137–149; die [Zahlen] sind Links auf die entsprechende Fachliteratur)

Class Agent Dose
 Symptomatic therapy: Benzodiazepines [33] Diazepam [28] 5-100 mg/day
Clonazepam [98, 127] 2.5–6 mg/day
Alprazolam 2–4 mg/day
Lorazepam 6 mg/day
 Muscle relaxants Tizanidine [127] 6–36 mg/day
Baclofen [157] 10–60 mg/day
ITB [151] 50–150 μg/day
Dantrolene 200–400 mg/day
Botulinum toxin A [7,46] Variable
 Cannabis THC-CBD [211] Variable
 Antiepileptic  drugs Levetiracetam [179]  500–1000 mg twice a day
Pregabaline 75–150 mg twice a day
Gabapentin [207] 300–900 mg three times day
Tiagabine [138] 4–8 mg once or twice a day
Valproate [190] 300–600 mg twice daily
Vigabatrin [208] 500–1500 mg twice daily
 Immunotherapy IVIg [56, 37] 1 g/kg body weight/month.
Rituximab [107] 2 infusions of 1 g each, every two weeks
Plasma exchange [125, 147] 5 PE in 1–2 weeks
Corticosteroids [68, 153] 50-60 mg/day
Mycophenolate mofetil [123] 2 g/day
Tacrolimus [142] 3 mg/day
Cyclophosphamide [209] 1-5 mg/kg/day
Azathioprine [192] 1–2.5 mg/kg/day
Methotrexate 15-20 mg/day
Interventional therapy Anesthesia [182, 77]  
Spinal cord Stimulation [204]